Anti-TRNAU1AP Antibody Picoband®

Enables RNA binding activity. Predicted to be involved in selenocysteine incorporation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. TRNAU1AP binds selenocysteine tRNA (tRNA-sec; see 165060) and is a component of the selenocysteine biosynthesis pathway.

Boster Bio Anti-TRNAU1AP Antibody Picoband® catalog # A15424-1. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1; KBTBD2; BKLHD1; KIAA1489

TRNAU1AP

54952

Q9NX07

Human

No cross-reactivity with other proteins.

E.coli-derived human TRNAU1AP recombinant protein (Position: R21-E282) .

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

WB, ELISA

Cell Biology

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

1. Ding, F., Grabowski, P. J. Identification of a protein component of a mammalian tRNA-Sec complex implicated in the decoding of UGA as selenocysteine. RNA 5: 1561-1569, 1999. 2. Gross, M. B. Personal Communication. Baltimore, Md. 10/28/2021. 3. Hu, X., Luo, J., Lai, H., Li, M., Zheng, X., Nie, T., Li, F., Li, H. Knockdown of Trnau1ap inhibits the proliferation and migration of NIH3T3, JEG-3 and Bewo cells via the PI3K/Akt signaling pathway. Biochem. Biophys. Res. Commun. 503: 521-527, 2018.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A15424-1

24145 MW

40 kDa

Kelch repeat and BTB domain containing 2

Cul3-RING ubiquitin ligase complex.

Transmembrane protein 240

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.