Anti-TRPV5 Konijn Monoklonale Antilichaam

Boster Bio Anti-TRPV5 Rabbit Monoclonal Antibody catalog # M03218. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform ; MLC-2 ; MLC-2v; Cardiac myosin light chain 2 ; Myosin light chain 2, slow skeletal/ventricular muscle isoform ; MLC-2s/v ; Ventricular myosin light chain 2 ; MYL2 ; MLC2

TRPV5

56302

Q9NQA5

Human, Mouse, Rat

A synthesized peptide derived from human TRPV5

Clone: 27T91

In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain. .

WB, IHC

Motor Proteins, Myosin, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Contractile protein that plays a role in heart development and function (By similarity) . Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity) . During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M03218

18789 MW

100 kDa

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

Cytoplasm, myofibril, sarcomere, A band .

T-cell surface glycoprotein CD3 zeta chain

IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.