Anti-Tryptase alfa/beta-1 TPSAB1 Antilichaam

Boster Bio Anti-Tryptase alpha/beta-1 TPSAB1 Antibody catalog # A08039. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Tryptase alpha/beta-1; Tryptase-1;3.4.21.59; Tryptase I; Tryptase alpha-1; TPSAB1; TPS1, TPS2, TPSB1

TPSAB1

Q15661

Human, Mouse, Rat

A synthetic peptide of human TPSAB1 (NP_003285.2) .

Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level) .

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315) .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A08039

30515 MW

WB: 1:500-1:2000

Tryptase alpha/beta-1

Secreted. Released from the secretory granules upon mast cell activation. .

Tryptase alpha/beta-1

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2