Anti-TTC29 Antibody Picoband® 31.0550 Vervoeging

Involved in cilium movement and cilium organization. Located in sperm flagellum. Implicated in spermatogenic failure 42.

Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; PYROXD1

TTC29

83894

Q8NA56

Human

No cross-reactivity with other proteins.

E.coli-derived human TTC29 recombinant protein (Position: D40-R460) .

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Flow Cytometry

Cell Biology

Immunogen affinity purified.

Liquid

Involved in cellular response to oxidative stress.

1. Gross, M. B. Personal Communication. Baltimore, Md. 1/10/2019. 2. Liu, C., He, X., Liu, W., Yang, S., Wang, L., Li, W., Wu, H., Tang, S., Ni, X., Wang, J., Gao, Y., Tian, S., and 12 others. Bi-allelic mutations in TTC29 cause male subfertility with asthenoteratospermia in humans and mice. Am. J. Hum. Genet. 105: 1168-1181, 2019. 3. Lores, P., Dacheux, D., Kherraf, Z.-E., Nsota Mbango, J.-F., Coutton, C., Stouvenel, L., Ialy-Radio, C., Amiri-Yekta, A., Whitfield, M., Schmitt, A., Cazin, C., Givelet, M., and 24 others. Mutations in TTC29, encoding an evolutionarily conserved axonemal protein, result in asthenozoospermia and male infertility. Am. J. Hum. Genet. 105: 1148-1167, 2019.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

24145 MW

6

Pyridine nucleotide-disulphide oxidoreductase domain 1

Nucleus. Sarcomere.

Transmembrane protein 240

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.