Anti-UBA1/Ube1 Konijn Monoklonale Antilichaam

Boster Bio Anti-UBA1/Ube1 Rabbit Monoclonal Antibody catalog # M02810. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Ubiquitin-like modifier-activating enzyme 1;6.2.1.45 ; Protein A1S9; Ubiquitin-activating enzyme E1; UBA1; A1S9T, UBE1

UBA1

7317

P22314

Human, Mouse, Rat

A synthesized peptide derived from human UBA1

Clone: IAC-21

Detected in erythrocytes (at protein level) . Ubiquitous. .

WB, IHC, ICC, IF, Flow Cytometry

Cell Biology, Epigenetics and Nuclear Signaling, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers

Affinity-chromatography

0.5mg/ml

Liquid

Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin- proteasome system (PubMed:1606621, PubMed:1447181) . Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (PubMed:1447181) . Essential for the formation of radiation- induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (PubMed:22456334) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02810

117849 MW

118 kDa

Ubiquitin-like modifier-activating enzyme 1

Cytoplasm . Mitochondrion . Nucleus .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.