Anti-UBR5 Antibody Picoband®

This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

Boster Bio Anti-UBR5 Antibody Picoband® catalog # A03160-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

UBR5; EDD; EDD1; HYD; KIAA0896; E3 ubiquitin-protein ligase UBR5; EC 2.3.2.26; E3 ubiquitin-protein ligase, HECT domain-containing 1; HECT-type E3 ubiquitin transferase UBR5; Hyperplastic discs protein homolog; hHYD; Progestin-induced protein

UBR5

51366

O95071

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human UBR5 recombinant protein (Position: K31-K761) .

WB, Flow Cytometry, ELISA

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Callaghan, M. J., Russell, A. J., Woollatt, E., Sutherland, G. R., Sutherland, R. L., Watts, C. K. W. Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs. Oncogene 17: 3479-3491, 1998. 2. Clancy, J. L., Henderson, M. J., Russell, A. J., Anderson, D. W., Bova, R. J., Campbell, I. G., Choong, D. Y. H., Macdonald, G. A., Mann, G. J., Nolan, T., Brady, G., Olopade, O. I., Woollatt, E., Davies, M. J., Segara, D., Hacker, N. F., Henshall, S. M., Sutherland, R. L., Watts, C. K. W. EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer. Oncogene 22: 5070-5081, 2003. 3. Henderson, M. J., Russell, A. J., Hird, S., Munoz, M., Clancy, J. L., Lehrbach, G. M., Calanni, S. T., Jans, D. A., Sutherland, R. L., Watts, C. K. W. EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response. J. Biol. Chem. 277: 26468-26478, 2002.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A03160-1

309 kDa

309 kDa

6

Ubiquitin protein ligase E3 component n-recognin 5

E3 ubiquitin-protein ligase UBR5

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.