Anti-Uroplakin-1b UPK1B Antilichaam

Uroplakin-1B (UPK1B) is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. UPK1B is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins and may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.

Boster Bio Anti-Uroplakin-1b UPK1B Antibody (Catalog # A10230) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

UPIB, UPK1, TSPAN20, Uroplakin-1b, Tetraspanin-20, UP1b

UPK1B

O75841

Human, Mouse, Rat

At least two isoforms of UPK1B are known to exist; this antibody will recognize both isoforms. UPK1B antibody is predicted to not cross-react with other tetraspanin protein family members.

UPK1B antibody was raised against a 17 amino acid synthetic peptide near the center of human UPK1B. The immunogen is located within amino acids 110 - 160 of UPK1B.

Bladder epithelium.

ELISA, WB, IHC-P, IF

Signal Transduction

UPK1B Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Component of the asymmetric unit membrane (AUM) ; a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity) . .

UPK1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A10230

29643 MW

Uroplakin 1B

Membrane; Multi-pass membrane protein.

Bovine

Uroplakin 1B

IgG

UPK1B Antibody is supplied in PBS containing 0.02% sodium azide.