Anti-USP26 Antibody Picoband® fluoro550 Vervoeging

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility.

Protein SOX-15; Protein SOX-12; Protein SOX-20; SOX15; SOX12; SOX20; SOX26; SOX27

USP26

83844

Q9BXU7

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human USP26 recombinant protein (Position: M1-K762) .

Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

Flow Cytometry

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Immunogen affinity purified.

Liquid

Binds to the 5'-AACAAT-3' sequence.

1. Ma, Q., Li, Y., Guo, H., Li, C., Chen, J., Luo, M., Jiang, Z., Li, H., Gui, Y. A novel missense mutation in USP26 gene is associated with nonobstructive azoospermia. Reprod. Sci. 23: 1434-1441, 2016. 2. Ravel, C., El Houate, B., Chantot, S., Lourenco, D., Dumaine, A., Rouba, H., Bandyopadahyay, A., Radhakrishna, U., Das, B., Sengupta, S., Mandelbaum, J., Siffroi, J. P., McElreavey, K. Haplotypes, mutations and male fertility: the story of the testis-specific ubiquitin protease USP26. Molec. Hum. Reprod. 12: 643-646, 2006. 3. Stouffs, K., Lissens, W., Tournaye, H., Van Steirteghem, A., Liebaers, I. Possible role of USP26 in patients with severely impaired spermatogenesis. Europ. J. Hum. Genet. 13: 336-340, 2005.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

49229 MW

6

SRY-box 15

Nucleus.

Chromaffin granule amine transporter

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.