Anti-USP28 Monoklonale Antilichaam

Boster Bio Anti-USP28 Monoclonal Antibody catalog # M05040. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Polypyrimidine tract-binding protein 2; Neural polypyrimidine tract-binding protein; Neurally-enriched homolog of PTB; PTB-like protein; PTBP2; NPTB, PTB, PTBLP

USP28

57646

Q96RU2

Human

A synthesized peptide derived from human USP28 Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN.

Clone: ADDO-21

Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non- neuronal tissues. .

WB, ICC, IF, Flow Cytometry

Apoptosis, Cancer, Cell Biology, Cell Death, Deubiquitination, Epigenetics and Nuclear Signaling, Invasion/Microenvironment, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers

Affinity-chromatography

0.5mg/ml

Liquid

RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M05040

57491 MW

100 kDa

Polypyrimidine tract-binding protein 2

Nucleus .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.