Anti-VE-Cadherin Cdh5-Rabbit Monoklonale Antilichaam

Boster Bio Anti-VE-Cadherin Cdh5-Rabbit Monoclonal Antibody catalog # M02632. Tested in WB, ICC/IF, IP applications. This antibody reacts with Mouse.

Cadherin-5; Vascular endothelial cadherin; VE-cadherin; CD144; Cdh5

Cdh5

12562

P55284

Mouse

A synthesized peptide derived from mouse VE Cadherin

Clone: IIC-3

Keratinocytes of epidermis and other stratified squamous epithelia.

WB, ICC, IF, IP

Atherosclerosis, Cadherins, Cancer, Cardiovascular, Cell Adhesion, Cell Adhesion Molecules, Cytoskeleton/ECM, Invasion/Microenvironment, Signal Transduction, Vascular Inflammation, Vasculature

Affinity-chromatography

0.5mg/ml

Liquid

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02632

87903 MW

45 kDa

Cadherin-5

Cell junction . Cell membrane ; Single-pass type I membrane protein . Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions (By similarity) . .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.