Anti-VPS26B Antilichaam

Boster Bio Anti-VPS26B Antibody catalog # A12325. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Vacuolar protein sorting-associated protein 26B; Vesicle protein sorting 26B; VPS26B

VPS26B

Q4G0F5

Human, Mouse

The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280

WB, ELISA

Immunogen affinity purified

1 mg/mL

Liquid

Acts as component of the retromer cargo-selective complex (CSC) . The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1 (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A12325

39155 MW

Vacuolar protein sorting-associated protein 26B

Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity) . .

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.