Anti-WDR26 Antibody Picoband® Biotin Conjugated

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene.

WDR26; CDW2; MIP2; PRO0852; WD repeat-containing protein 26; CUL4- and DDB1-associated WDR protein 2; Myocardial ischemic preconditioning up-regulated protein 2

WDR26

80232

Q9H7D7

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human WDR26 recombinant protein (Position: Q142-E583) . Human WDR26 shares 99.5% and 98.6% amino acid (aa) sequence identity with mouse and rat WDR26, respectively.

WB, IHC, ELISA

Immunogen affinity purified.

Liquid

1. Goto, T., Matsuzawa, J., Iemura, S., Natsume, T., Shibuya, H. WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway. FEBS Lett. 590: 1291-1303, 2016. 2. Skraban, C. M., Wells, C. F., Markose, P., Cho, M. T., Nesbitt, A. I., Au, P. Y. B., Begtrup, A., Bernat, J. A., Bird, L. M., Cao, K., de Brouwer, A. P. M., Denenberg, E. H., and 28 others. WDR26 haploinsufficiency causes a recognizable syndrome of intellectual disability, seizures, abnormal gait, and distinctive facial features. Am. J. Hum. Genet. 101: 139-148, 2017. 3. Sun, Z., Smrcka, A. V., Chen, S. WDR26 functions as a scaffolding protein to promote G-beta-gamma-mediated phospholipase C beta-2 (PLC-beta-2) activation in leukocytes. J. Biol. Chem. 288: 16715-16725, 2013.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

72 kDa

WD repeat domain 26

WD repeat-containing protein 26

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.