Anti-WDR37 Antibody Picoband® fluoro488 Vervoeging

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

WDR37; KIAA0982; WD repeat-containing protein 37

WDR37

22884

Q9Y2I8

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human WDR37 recombinant protein (Position: D161-Q451) . Human WDR37 shares 96.2% amino acid (aa) sequence identity with mouse WDR37.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Kanca, O., Andrews, J. C., Lee, P.-T., Patel, C., Braddock, S. R., Slavotinek, A. M., Cohen, J. S., Gubbels, C. S., Aldinger, K. A., Williams, J., Indaram, M., Fatemi, A., and 16 others. De novo variants in WDR37 are associated with epilepsy, colobomas, dysmorphism, developmental delay, intellectual disability, and cerebellar hypoplasia. Am. J. Hum. Genet. 105: 413-424, 2019. Note: Erratum: Am. J. Hum. Genet. 105: 672-674, 2019. 2. Reis, L. M., Sorokina, E. A., Thompson, S., Muheisen, S., Velinov, M., Zamora, C., Aylsworth, A. S., Semina, E. V. De novo missense variants in WDR37 cause a severe multisystemic syndrome. Am. J. Hum. Genet. 105: 425-433, 2019. 3. Stumpf, A. M. Personal Communication. Baltimore, Md. 09/25/2019.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

55 kDa

6

WD repeat domain 37

WD repeat-containing protein 37

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.