Anti-WDR77 Antibody Picoband® fluoro488 Vervoeging

Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene. The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.

Vesicular acetylcholine transporter; VAChT; Solute carrier family 18 member 3; SLC18A3; VACHT

WDR77

79084

Q9BQA1

Human

No cross-reactivity with other proteins.

E.coli-derived human WDR77 recombinant protein (Position: A13-A295) .

Peripheral and central cholinergic nervous systems. .

Flow Cytometry

Neuroscience, Neurotransmitter

Immunogen affinity purified.

Liquid

Involved in acetylcholine transport into synaptic vesicles. .

1. Friesen, W. J., Wyce, A., Paushkin, S., Abel, L., Rappsilbers, J., Mann, M., Dreyfuss, G. A novel WD repeat protein component of the methylosome binds Sm proteins. J. Biol. Chem. 277: 8243-8247, 2002. 2. Furuno, K., Masatsugu, T., Sonoda, M., Sasazuki, T., Yamamoto, K. Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitro. Biochem. Biophys. Res. Commun. 345: 1051-1058, 2006. 3. Gross, M. B. Personal Communication. Baltimore, Md. 3/2/2018.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

56903 MW

6

Vesicular acetylcholine transporter

Membrane ; Multi-pass membrane protein .

Vesicular acetylcholine transporter

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.