Anti-ZG16 Antilichaam

Zymogen granule protein 16 (ZG16) has a Jacalin-like lectin domain, which is mainly expressed by mucus-secreting cells, including goblet cells in the intestine. It's reported that ZG16 expression was significantly decreased in colorectal cancer compared to normal tissue. ZG16 gene expression and copy number variations (CNV) were associated with multiple molecular and clinicopathological features of CRC including MSI, MLH1 silencing and so on. It's found that ZG16 is negatively correlated with lymphatic invasive and distant metastasis. Besides, overexpression of ZG16 blocks PD-L1 expression in colorectal cancer, and promotes NK cells survival and proliferation. Very importantly, ZG16 suppresses colorectal tumor growth via the immune system. (PMID: 33360840, 21893569)

Boster Bio Anti-ZG16 Antibody catalog # A09278-1. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

FLJ43571; FLJ92276; hZG16; JCLN; JCLN1

ZG16

O60844

Human, Mouse

E.coli-derived human ZG16 recombinant protein (Position: T3-S165) .

WB, IHC, IF, ELISA

Immunogen affinity purified.

500 μg/mL

Liquid

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A09278-1

Zymogen granule protein 16

Zymogen granule membrane protein 16

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.