Anti-Zinc-vingereiwit 346 ZNF346 Antilichaam

ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.

Boster Bio Anti-Zinc finger protein 346 ZNF346 Antibody (Catalog # A09984) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

JAZ, Zfp346, JAZ, Zinc finger protein 346, Just another zinc finger protein

ZNF346

Q9UL40

Human, Mouse, Rat

ZNF346 antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human ZNF346. The immunogen is located within amino acids 70 - 120 of ZNF346.

ELISA, WB

Cancer, Cell Cycle

ZNF346 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity (PubMed:24521053) . May bind to specific miRNA hairpins (PubMed:28431233) .

ZNF346 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A09984

32933 MW

Zinc finger protein 346

Nucleus, nucleolus

Zinc finger protein 346

IgG

ZNF346 Antibody is supplied in PBS containing 0.02% sodium azide.