Anti-ZIP10 SLC39A10 Antilichaam

ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.

Boster Bio Anti-ZIP10 SLC39A10 Antibody (Catalog # A09043) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Zinc transporter ZIP10; Solute carrier family 39 member 10; Zrt- and Irt-like protein 10; ZIP-10; SLC39A10; KIAA1265, ZIP10

SLC39A10

Q9ULF5

Human, Mouse, Rat

This antibody will not cross-react with the zinc transporter ZIP11.

ZIP10 antibody was raised against a 17 amino acid synthetic peptide near the center of the human ZIP10. The immunogen is located within amino acids 490 - 540 of ZIP10.

High expression in placenta, skeletal muscle, kidney and pancreas tissues. Absent or very faint expression in heart, brain, lung and liver. Expressed during adipogenic differentiation of mesenchymal stem cells (at protein level) .

ELISA, WB, IHC-P

Homeostasis

ZIP10 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

May act as a zinc-influx transporter.

ZIP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A09043

94132 MW

Solute carrier family 39 (zinc transporter), member 10

Membrane ; Multi-pass membrane protein .

Solute carrier family 39 (zinc transporter), member 10

IgG

ZIP10 Antibody is supplied in PBS containing 0.02% sodium azide.