Anti-ZMYND8 Antibody Picoband® fluoro488 Vervoeging

Protein kinase C-binding protein 1 is an enzyme that in humans is encoded by the ZMYND8 gene. The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.

Intraflagellar transport protein 88 homolog; Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10; TPR repeat protein 10; IFT88; TG737; TTC10

ZMYND8

23613

Q9ULU4

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human ZMYND8 recombinant protein (Position: M1-Q1087) .

Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.

Flow Cytometry

Cell Adhesion Proteins, ECM Proteins, Neuroscience

Immunogen affinity purified.

Liquid

Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.

1. Fossey, S. C., Kuroda, S., Price, J. A., Pendleton, J. K., Freedman, B. I., Bowden, D. W. Identification and characterization of PRKCBP1, a candidate RACK-like protein. Mammalian Genome 11: 919-925, 2000. 2. Gross, M. B. Personal Communication. Baltimore, Md. 3/28/2014. 3. Shen, H., Xu, W., Guo, R., Rong, B., Gu, L., Wang, Z., He, C., Zheng, L., Hu, X., Hu, Z., Shao, Z.-M., Yang, P., Wu, F., Shi, Y. G., Shi, Y., Lan, F. Suppression of enhancer overactivation by a RACK7-histone demethylase complex. Cell 165: 331-342, 2016.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

104553 MW

6

Intraflagellar transport 88

Centriole. Cilium basal body. Centrosome. Cilium. Cytoplasm. Flagellum.

AP-2 complex subunit beta

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.