Anti-ZNRF2 Antilichaam

Boster Bio Anti-ZNRF2 Antibody (Catalog# A11505) . Tested in IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse.

ZNRF2; RNF202; E3 ubiquitin-protein ligase ZNRF2; Protein Ells2; RING finger protein 202; Zinc/RING finger protein 2

ZNRF2

Q8NHG8

Human, Mouse

A peptide derived from human ZNRF2. Immunogen sequence location: 161-210

Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney.

IHC, ICC, IF, ELISA

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ring Finger E3 Ligase, Ubiquitin E3 Enzymes

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Liquid

May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A11505

24115 MW

E3 ubiquitin-protein ligase ZNRF2

Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein. Present in presynaptic plasma membranes in neurons.

Rabbit IgG

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.