Anti-ZPI/SERPINA10 Antibody Picoband® fluoro594 Vervoeging

The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.

Phosphopantothenate--cysteine ligase, Phosphopantothenoylcysteine synthetase, PPC synthetase, PPCS, COAB

SERPINA10

51156

Q9UK55

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human ZPI/SERPINA10 recombinant protein (Position: L128-E427) .

Expressed in heart, placenta, skeletal muscle kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Expressed in lung endothelial and smooth muscle cells (at protein level) .

Flow Cytometry

Amino Acid Metabolism, Amino Acids, Cofactors, Vitamins/Minerals, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Vitamins/Minerals

Immunogen affinity purified.

Liquid

Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.

1. Han, X., Fiehler, R., Broze, G. J., Jr. Isolation of protein Z-dependent plasma protease inhibitor. Proc. Nat. Acad. Sci. 95: 9250-9255, 1998. 2. Han, X., Huang, Z. F., Fiehler, R., Broze, G. J., Jr. The protein Z-dependent protease inhibitor is a serpin. Biochemistry 38: 11073-11078, 1999. 3. New, L., Liu, K., Kamali, V., Plowman, G., Naughton, B. A., Purchio, A. F. cDNA cloning of rasp-1, a novel gene encoding a plasma protein associated with liver regeneration. Biochem. Biophys. Res. Commun. 223: 404-412, 1996.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

48608 MW

6

Phosphopantothenoylcysteine synthetase

Cytosol.

Serine protease HTRA3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.