Antibacterieel middel 309
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Antibacterial agent 309 (Compound C9) is an antibacterial agent, substrate of AcrB efflux pump. Antibacterial agent 309 promotes FtsZ polymerization. Antibacterial agent 309 demonstrates antibacterial activity against Erythromycin -resistant S. pyogenes 2 (MIC = 0.25 μg/mL), Penicillin-resistant S. aureus CI (MIC = 0.125 μg/mL), Penicillin-resistant S. epidermidis (MIC = 2 μg/mL). Antibacterial agent 309 exhibits weak antibacterial activity against the wild-type E. coli BW25113 MIC = 256 μg/mL).
12352005
Bacterial
Anti-infection
Infection
C[N+]1=C(/C=C/C2=CC=C(F)C=C2)N=C(/C=C3SC(C=CC=C4)=C4N\3C)C5=CC=CC=C51.[I-]
C26H21FIN3S
553.43
[1]Zhang S, et al. Novel 1-Methylquinazoline and 1-Methylquinoxaline derivatives targeting FtsZ protein: Potent antibacterial agents against gram-positive bacteria. Bioorg Chem. 2025 Dec;167:109282.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-180273/
Reference compound1
No Development Reported
Beschrijving
Antibacterial agent 309 (Compound C9) is an antibacterial agent, substrate of AcrB efflux pump. Antibacterial agent 309 promotes FtsZ polymerization. Antibacter
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