Antilichaam

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

7372

P11172

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human UMPS (NP_000364.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

HT-29

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 57kDa

IgG

UMPS

U-87MG

HeLa

LO2

Mouse brain

Mouse kidney

Uridine monophosphate synthetase

Homo sapiens

UMPS, OPRT, RP11-71H17.9

WB, IF

Liquid