Antineurine (NTN) Antilichaam

Neurturin (NTN) is a member of the GDNF family of neurotrophic factors. This protein is a potent survival factor for several populations of central and peripheral neurons in mature and developing rodents. FUNCTION: Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells. SUBUNIT: Homodimer; disulfide-linked. SUBCELLULAR LOCATION: Secreted protein. DISEASE: Defects in NRTN are a cause of Hirschsprung disease (HSCR) . In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction. SIMILARITY: Belongs to the TGF-beta family. GDNF subfamily.

Our Anti-Neurturin mouse monoclonal primary antibody detects human Neurturin , and is igg. It is validated for use in WB.

Our Anti-Neurturin mouse monoclonal primary antibody detects human Neurturin, and is IgG. It is validated for use in WB.

Q99748

Human

Recombinant human NRTN protein produced using CHO-based suspension cell line. Protein was purified from the cell culture supernatant.

Neurturin

1B11

Unconjugated

WB

IgG

PBS pH 7.4, with 0.1% sodium azide

For research use only.

25°C (ambient)

Store at -20°C or -70°C upon receipt. After opening divide antibody into smaller aliquots and store at -20°C or -70°C for up to six months. Avoid multiple freeze-thaw cycles as product degradation may result.

Protein G purified IgG

1:5000-1:10000

Human NTN (Neurturin) .

Mouse

Liquid

IgG1

Human