Antineurine (NTN) Antilichaam

Neurturin (NTN) is a member of the GDNF family of neurotrophic factors. This protein is a potent survival factor for several populations of central and peripheral neurons in mature and developing rodents. FUNCTION: Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells. SUBUNIT: Homodimer; disulfide-linked. SUBCELLULAR LOCATION: Secreted protein. DISEASE: Defects in NRTN are a cause of Hirschsprung disease (HSCR) . In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction. SIMILARITY: Belongs to the TGF-beta family. GDNF subfamily.

Our Anti-Neurturin (NTN) rabbit polyclonal primary antibody detects human Neurturin (NTN), and is igg. It is validated for use in WB.

Our Anti-Neurturin (NTN) rabbit polyclonal primary antibody detects human Neurturin (NTN), and is IgG. It is validated for use in WB.

Q99748

Human

Recombinant human NRTN protein produced using CHO-based suspension cell line. Protein was purified from the cell culture supernatant.

Neurturin (NTN)

Unconjugated

WB

IgG

Concentrated ammonium sulfate in PBS pH 7.4.

For research use only.

2-8°C (on cold packs)

Store at 2-8°C upon receipt. As product is (NH4) 2SO4 (ammonium sulfate) precipitate, mix well by pipetting or vortexing prior to use.

Protein G purified IgG

1:500-1:1000

Antibody does not show cross-reactivity to other GDNF-family proteins.

Rabbit

Liquid

IgG

Human