Antiparathyroïd Hormone Receptor 1 Monoklonale Antilichaam

Boster Bio Anti-Parathyroid Hormone Receptor 1 Monoclonal Antibody catalog # M01588. Tested in WB, IP applications. This antibody reacts with Human.

Claudin-1; Senescence-associated epithelial membrane protein; CLDN1; CLD1, SEMP1; UNQ481/PRO944

PTH1R

5745

Q03431

Human

A synthesized peptide derived from human Parathyroid Hormone Receptor 1 Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

Clone: AEHO-16

Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis. .

WB, IP

Endocrine System, Growth Factors/Hormones, Neuroscience, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an in effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (PubMed:23407391) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01588

22744 MW

47 kDa

Claudin-1

Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.