Antipreseniline 1 loopgebied Antilichaam

Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot) .

Our Anti-Presenilin 1 loop region rabbit polyclonal primary antibody detects human and mouse Presenilin 1 loop region , and is igg. It is validated for use in WB.

Our Anti-Presenilin 1 loop region rabbit polyclonal primary antibody detects human and mouse Presenilin 1 loop region, and is IgG. It is validated for use in WB.

Presenilin 1; PS-1; Protein S182; PS1-CTF12; PSEN1; AD3; PS1; PSNL1

P49768

Human and Mouse

A synthetic peptide (GDPEAQRRVSKNSKYNA-C) corresponding to human PS1 [301-317] in the loop region conjugated via additional C-terminal Cys to Diphtheria toxoid.

Presenilin 1 loop region

Unconjugated

WB

IgG

Lyophilized from PBS, pH 7.4. Contains no preservative.

19 kDa, 45 kDa (See application details.)

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 500 μL sterile-filtered 1X PBS, pH 7.2-7.6. Centrifuge to remove any insoluble material. Short term storage at 2-8°C for one week. At -20°C as an undiluted liquid for up to 12 months.

Protein G purified IgG

0.7361111111111112

Confirmed by Western blotting using transfected cells, presenilin 1 knock-out mouse cells and mouse and human brain.

Rabbit

Lyophilized

IgG

Human