Antipreseniline 1 (PS-1) Antilichaam

Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot) .

Our Anti-Presenilin 1 (PS-1) rabbit polyclonal primary antibody detects human and mouse Presenilin 1 (PS-1), and is igg. It is validated for use in WB, IF.

Our Anti-Presenilin 1 (PS-1) rabbit polyclonal primary antibody detects human and mouse Presenilin 1 (PS-1), and is IgG. It is validated for use in WB.

Presenilin 1; PS-1; Protein S182; PS1-CTF12; PSEN1; AD3; PS1; PSNL1

P49768

Human and Mouse

A synthetic peptide corresponding to a region (1-20 aa) from the N-terminus of human Presenilin 1 conjugated to Diptheria toxoid.

Presenilin 1 (PS-1)

Unconjugated

WB, IF

IgG

Lyophilized from PBS, pH 7.4. Contains no preservative.

29 kDa, 45 kDa (see application details)

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 500 μL sterile-filtered 1X PBS, pH 7.2-7.6. Centrifuge to remove any insoluble material. Short term storage at 2-8°C for one week. At -20°C as an undiluted liquid for up to 12 months.

Protein G purified IgG

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1.4305555555555556

Specificity confirmed by WB and IF using transfected cells, Presenilin 1 knock-out mouse cells, mouse and human brain.

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Rabbit

Lyophilized

IgG

Human