Antiprotein SOGA1 SOGA1 Antilichaam

The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1) . SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2) . SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2) . Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3) .

Boster Bio Anti-Protein SOGA1 SOGA1 Antibody (Catalog # A13046) . Tested in ELISA, WB, IF applications. This antibody reacts with Human.

SOGA, KIAA0889, C20orf117, SOGA, Protein SOGA1, SOGA family member 1, 80-kDa SOGA fragment

SOGA1

O94964

Human

SOGA1 antibody is human specific. At least four isoforms of SOGA1 are known to exist.

SOGA1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SOGA. The immunogen is located within the last 50 amino acids of SOGA1 .

ELISA, WB, IF

Autophagy

SOGA1 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner. .

SOGA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

https://www.bosterbio.com/msds?sku=A13046

159760 MW

Suppressor of glucose, autophagy associated 1

C-terminal 80 kDa form: Secreted . Secreted in primary hepatocyte-conditioned media. .

Mouse

Suppressor of glucose, autophagy associated 1

IgG

SOGA1 Antibody is supplied in PBS containing 0.02% sodium azide.