Antisecurinemonoklonale antilichamen

Boster Bio Anti-Securin Monoclonal Antibody catalog # M02099. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Actin-related protein 2/3 complex subunit 5; Arp2/3 complex 16 kDa subunit; p16-ARC; ARPC5; ARC16

PTTG1

9232

O95997

Human

A synthesized peptide derived from human Securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.

Clone: ADFH-16

Predominantly in urogenital tissues.

WB, IHC, ICC, IF, IP, Flow Cytometry

Cancer, Epigenetics and Nuclear Signaling, Nuclear Import/Export, Protein Trafficking, Signal Transduction, Transcription, Tumor Biomarkers

Affinity-chromatography

0.5mg/ml

Liquid

Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02099

16320 MW

26 kDa

Actin-related protein 2/3 complex subunit 5

Cytoplasm, cytoskeleton . Cell projection .

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.