Antisodium/waterstofwisselaar 2 SLC9A2 Antibody Picoband® fluoro550 Vervoeging

Sodium– hydrogen exchanger 2, also called SLC9A2 or NHE2 is a protein that in humans is encoded by the SLC9A2 gene. This gene is mapped to 2q12.1. The Na+/H+ exchangers (NHE) are membrane proteins involved in cell volume. The exchanger (which they called NHE2) is found in several tissues, including intestine and kidney, and is highly expressed in villus and distal convoluted tubules. This gene is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. It seems to play an important role in colonic sodium absorption.

Sodium/hydrogen exchanger 2; Na (+) /H (+) exchanger 2; NHE-2; Solute carrier family 9 member 2; SLC9A2; NHE2

SLC9A2

6549

Q9UBY0

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human SLC9A2, different from the related rat and mouse sequences by two amino acids.

Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.

Flow Cytometry

Cardiovascular, Cell Biology, Protease Inhibitors, Proteolysis/Ubiquitin

Immunogen affinity purified.

Liquid

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.

1. Ghishan, F. K., Knobel, S. M., Summar, M. Molecular cloning, sequencing, chromosomal localization, and tissue distribution of the human Na+/H+ exchanger (SLC9A2) . Genomics 30: 25-30, 1995. 2. Pathak, B. G., Shull, G. E., Jenkins, N. A., Copeland, N. G. Mouse chromosomal location of four Na/H exchanger isoform genes. Genomics 31: 261-263, 1996.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

91520 MW

No cross reactivity with other proteins.

6

Sodium/hydrogen exchanger 2

Membrane; Multi-pass membrane protein.

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

Sodium/hydrogen exchanger 2

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.