Antisortering nexin-18 SNX18 Antilichaam

Boster Bio Anti-Sorting nexin-18 SNX18 Antibody catalog # A09010. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Sorting nexin-18; SH3 and PX domain-containing protein 3B; Sorting nexin-associated Golgi protein 1; SNX18; SH3PXD3B, SNAG1

SNX18

Q96RF0

Human, Mouse, Rat

Recombinant protein of human SNX18

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09010

68894 MW

WB: 1:500-1:2000

Sorting nexin-18

Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin- coated pits at a late stage of clathrin-coated vesicle formation.

Sorting nexin-18

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2