Antispectrine (alfa en bèta) Monoklonale Antilichaam (Kloon: SB-SP1)

Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2. Spectrin mutations cause spinocerebellar ataxia type 5.

Erythroid spectrin beta ; Sptb ; LOC314251

Sptb

314251

Q6XDA0

Human

Human erythrocyte spectrin.

Spectrin alpha chain, erythrocytic 1; Spectrin beta chain, erythrocytic

SB-SP1

WB

Ascites

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Western blot : 2-4μg/ml

Mouse IgG1