Antisynaptophysin Syp Antilichaam (Monoclonal, SVP-38)

Synaptophysin (SYP) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells. Ozcelik et al. (1990) concluded that the gene has 7 exons distributed over about 20 kb. SYP mapped the SYP locus to Xp11.23-p11.22. Regionalization of the gene on the X chromosome was also done with hamster/human hybrid cells in which various portions of the human X chromosome were present.

Boster Bio Anti-Synaptophysin Syp Antibody (Monoclonal, SVP-38) catalog # MA1091. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Synaptophysin; Major synaptic vesicle protein p38; Syp

SYP

Human (6855), Mouse (20977), Rat (24804)

P07825

Human, Rat

No cross-reactivity with other proteins

Rat retina synaptosome.

Clone: SVP-38

Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.

IHC, WB

Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Plasma Membrane, Signal Transduction, Subcellular Markers, Tags & Cell Markers

Ascites

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Lyophilized

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity) . .

1. McMahon, H. T.; Bolshakov, V. Y.; Janz, R.; Hammer, R. E.; Siegelbaum, S. A.; Sudhof, T. C. : Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release. Proc. Nat. Acad. Sci. 93: 4760-4764, 1996. 2. Cremin, S. M.; Greer, W. L.; Bodok-Nutzati, R.; Schwartz, M.; Peacocke, M.; Siminovitch, K. A. : Linkage of Wiskott-Aldrich syndrome with three marker loci, DXS426, SYP and TFE3, which map to the Xp11.3-p11.22 region. Hum. Genet. 92: 250-253, 1993. 3. Ozcelik, T.; Lafreniere, R. G.; Archer, B. T., III; Johnston, P. A.; Willard, H. F.; Francke, U.; Sudhof, T. C. : Synaptophysin: structure of the human gene and assignment to the X chromosome in man and mouse. Am. J. Hum. Genet. 47: 551-561, 1990.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=MA1091

33311 MW

60 kDa

No cross reactivity with other proteins.

Synaptophysin

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.

Belongs to the synaptophysin/synaptobrevin family.

Synaptophysin

Mouse IgG1

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.