Antisyntafiline (N-terminaal gebied) Antilichaam

Synaptic vesicles are organelles situated at the distal terminus of the presynaptic neuron. The exocytosis of these vesicles requires docking at the plasma membrane, priming, and fusion. Fusion is mediated by a complex consisting of membrane components of both the synaptic vesicle and the synaptic plasma membrane. The fusion complex consists of the soluble NSF (N-ethyl-maleimide-sensitive factor), SNAPs (soluble NSF attachment proteins), and receptor proteins (SNAREs) that include synaptobrevin, synaptotagmin, syntaxin, and SNAP-25 (synaptosomal-associated protein of 25kDa) . Syntaxin-1 is a key component of the synaptic vesicle docking/fusion machinery which forms the SNARE complex with SNAP-25 and synaptobrevin. Syntaphilin is a brain-specific membrane-associated protein that can inhibit SNARE complex formation by binding free syntaxin-1.

Our Syntaphilin (N-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, mouse, and rat Syntaphilin (N-terminal region) and is protein a purified. It is great for use in ELISA, WB.

Our Syntaphilin (N-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects human, mouse, and rat Syntaphilin (N-terminal region) and is Protein A purified. It is great for use in WB.

SNPH

SNPH

O15079

Human, Mouse, and Rat

Clone M371 was generated from a sequence corresponding to amino acids in the N-terminal region of human syntaphilin. This sequence has high homology to mouse and rat syntaphilin.

Syntaphilin (N-terminal region)

M371

Unconjugated

ELISA, WB

Mitochondrial Biology, Neurodegenerative Disease, Amyotrophic Lateral Sclerosis (ALS), Vesicle Trafficking/Fusion

Protein A Purified

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

70

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Blue Ice

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Protein A purified culture supernatant.

1:500

This antibody detects a 70 kDa* protein corresponding to the molecular mass of Syntaphilin on SDS-PAGE immunoblots of adult mouse brain.

Western blots performed on each lot.

Mouse

Liquid

IgG1

Human

Quality Control: WB

AB_2193557