Antisyntaxine 6/STX6 Antibody Picoband® fluoro488 Vervoeging

Syntaxin-6 is a protein that in humans is encoded by the STX6 gene. Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation; retrograde transport, endosome to Golgi; and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome; perinuclear region of cytoplasm; and trans-Golgi network. Part of SNARE complex.

Semaphorin-3B; Sema A (V) ; Semaphorin-V; Sema V; SEMA3B; SEMA5; SEMAA

STX6

10228

O43752

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human Syntaxin 6/STX6 recombinant protein (Position: M1-A239) .

Expressed abundantly but differentially in a variety of neural and nonneural tissues.

Flow Cytometry

Adapters, Coat Proteins, Cytoplasmic, Protein Trafficking, Signal Transduction, Vesicle Transport

Immunogen affinity purified.

Liquid

Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

1. Advani, R. J., Bae, H.-R., Bock, J. B., Chao, D. S., Doung, Y.-C., Prekeris, R., Yoo, J.-S., Scheller, R. H. Seven novel mammalian SNARE proteins localize to distinct membrane compartments. J. Biol. Chem. 273: 10317-10324, 1998. 2. Charest, A., Lane, K., McMahon, K., Housman, D. E. Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6. J. Biol. Chem. 276: 29456-29465, 2001. 3. Cheng, J., Cebotaru, V., Cebotaru, L., Guggino, W. B. Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator. Molec. Biol. Cell 21: 1178-1187, 2010.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

104553 MW

6

Semaphorin 3B

Endoplasmic reticulum. Secreted.

AP-2 complex subunit beta

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.