Antitumornecrosefactorreceptor superfamilielid 19 (TROY) Antilichaam

FUNCTION: Can mediate activation of c-Jun and NF-kappa-B. May promote caspase-independent cell death. Isoform 2 and isoform 3 may act as decoy receptors. SUBUNIT: Associates with TRAF1, TRAF2, TRAF3 and TRAF5. SUBCELLULAR LOCATION: Isoform 1, isoform 3, isoform 4: Cell membrane; single-pass type I membrane protein (Probable) . Isoform 2: Secreted protein (Probable) . ALTERNATIVE PRODUCTS: 4 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Highly expressed in adult brain, and in embryos from day 11-17, but not earlier. Detected in embryonic brain and epithelium, and at lower levels in adult heart, lung and liver. In neonatal mice, mainly in hair follicles and neuron-like cells in the cerebellum, but not in the skin epidermis. Isoform 3 was found in embryonic day 17.5 skin but not in brain and liver. SIMILARITY: Contains 3 TNFR-Cys repeats.

Our Anti-Tumor necrosis factor receptor superfamily member 19 (TROY) rabbit polyclonal primary antibody detects mouse and rat Tumor necrosis factor receptor superfamily member 19 (TROY), and is whole serum. It is validated for use in IHC-Frozen.

Our Anti-Tumor necrosis factor receptor superfamily member 19 (TROY) rabbit polyclonal primary antibody detects mouse and rat Tumor necrosis factor receptor superfamily member 19 (TROY), and is whole serum. It is validated for use in IHC-Frozen.

Tumor necrosis factor receptor superfamily member 19; TNFRSF19; Toxicity and JNK inducer; TRADE

Q9JLL3

Mouse and Rat

A synthetic peptide (CRPHRF KEDWGFQK) as part of mouse TROY protein (aa: 75-88) conjugated to the immunogenic protein Blue Carrier Protein

Tumor necrosis factor receptor superfamily member 19 (TROY)

Unconjugated

IHC-Frozen

Whole serum

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

1:500-1:2000

Specificity for TROY was confirmed by IHC. This antiserum is known to react with rat TROY. Reactivity with other species have not yet been tested.

Rabbit

Lyophilized

Mixed

Mouse