ANXA6 Antilichaam - N-terminalgebied: HRP (ARP36583_T100-HRP)

Annexin A6

P68, p70, ANX6, CBP68, CPB-II

309

P08133

NP_001146

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA6

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.

UBC; MDM2; THOP1; PLS3; MTAP; IDH1; HPRT1; GOT1; ADSS; POLE3; NAMPT; UBE2H; ATP4A; METTL18; MLH1; SNCA; CUL5; SIRT7; PRKCA; TJP1; CD4; H2AFX; CDC73; TPD52; S100B; S100A1; RASA1; CR2; A2M; tax

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

ANXA6 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 86%; Dog: 86%; Guinea Pig: 85%; Horse: 86%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 85%; Rat: 93%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

74kDa

Cuschieri, J., et al., (2005) Surgery 138 (2), 158-164

Wet Ice

673

ANXA6

ANXA6

Rabbit

Annexin A6

NM_001155

ALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYE