![APC Recombinant antilichaam [5F2] (OACA12835)](/_ipx/q_80/productPlaceholder.webp)
APC Recombinant antilichaam [5F2] (OACA12835)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
APC regulator of WNT signaling pathway
Adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli (APC) ; adenomatous polyposis coli protein; APC, WNT signaling pathway regulator; BTPS2; deleted in polyposis 2.5; DESMD; DP2; DP2.5; DP3; epididymis secretory sperm binding protein; GS; PPP1R46; protein phosphatase 1, regulatory subunit 46; truncated adenomatosis polyposis coli; WNT signaling pathway regulator.
324
Human|Rat
A synthesized peptide derived from human APC
• Recombinant Monoclonal
Unconjugated
Recombinant Monoclonal Antibody
Affinity Purified
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
Liquid
-20°C or -80°C
APC
Adenomatous polyposis coli protein
APC
Beschrijving
APC Recombinant antilichaam [5F2] (OACA12835) Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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