APEH Antilichaam - Middengebied: FITC (ARP48182_P050-FITC)

N-acylaminoacyl-peptide hydrolase

APH, OPH, AARE, ACPH, D3S48E, D3F15S2, DNF15S2

327

P13798

NP_001631

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human APEH

APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

IST1; UBC; LGALS8; APEH; SNX6; CAND1; TOLLIP; CYHR1; JMJD6; HSPA4L; IPO7; DNM1L; VPS26A; NMI; H1FX; ZYX; TBCD; TARS; STAT1; SHMT2; SHMT1; PPM1G; SERPINE2; PAWR; LAMP2; KARS; HIST1H1C; GARS; CTTN; CARS; PREPL; SHBG; UBA5; TMEM62

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

81kDa

Wet Ice

732

APEH

APEH

Rabbit

Acylamino-acid-releasing enzyme

NM_001640

GSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSH