APG4B Antilichaam - C-terminaal gebied : HRP (ARP34434 P050-HRP)

ATG4 autophagy related 4 homolog B (S. cerevisiae)

APG4B, AUTL1

23192

Q9Y4P1

NP_037457

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human APG4B

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.

SUMO2; MAP1LC3B; MAP1LC3A; BAG3; ATG8; YWHAB; GABARAPL1; SQSTM1; UBC; GABARAPL2; ATG10; ATG3; AMBRA1; GABARAP; CAMKK2; ATG12; ULK1; STK3; KRT4; ANXA1; FBXW11; LINC00341

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

ATG4B is strongly supported by BioGPS gene expression data to be expressed in Raji

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

44kDa

Tanida, I., et al., (2004) J. Biol. Chem. 279 (35), 36268-36276

Wet Ice

393

ATG4B

ATG4B

Rabbit

Cysteine protease ATG4B

NM_013325

LGGALPMFELVELQPSHLACPDVLNLSLDSSDVERLERFFDSEDEDFEIL