Apicidin D2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Apicidin D2 (Compound 4), a fungal metabolite, is a Accessory gene regulator A (AgrA) quorum-sensing inhibitor. Apicidin D2 has anti-virulence activity. Apicidin D2 suppresses MRSA agr activation and shows potent inhibitory activities against all agr types in a nonbiocidal manner. Apicidin D2 can be used for MRSA infections research[1].
177562-78-6
12352100
Bacterial; Endogenous Metabolite
Anti-infection; Metabolic Enzyme/Protease
Infection
O=C1N2[C@@H](C(N[C@@H](CCCCC[C@@H](O)CC)C(N[C@@H](CC3=CN(OC)C4=C3C=CC=C4)C(N[C@H]1[C@@H](CC)C)=O)=O)=O)CCCC2
C34H51N5O6
625.80
[1]Parlet CP, et al. Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense. Cell Rep. 2019 Apr 2;27 (1) :187-198.e6.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W904855/
Reference compound1
No Development Reported
Beschrijving
Apicidin D2 (Compound 4), a fungal metabolite, is a Accessory gene regulator A (AgrA) quorum-sensing inhibitor. Apicidin D2 has anti-virulence activity. Apicidi
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