
Apilimod
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
541550-19-0
STA-5326
C11871-5mg
PIKfyve
PI3K/Akt/mTOR
CC1=CC (=CC=C1) C=NNC2=CC (=NC (=N2) OCCC3=CC=CC=N3) N4CCOCC4
C23H26N6O2
Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases. Apilimod (STA-5326) inhibits IL-12 with IC50 of 1 nM, 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs, human monocytes and mouse PBMCs, respectively. Apilimod (STA-5326) is also a cell permeable small molecule that specifically inhibits PIKfyve with IC50 of 14 nM.
3 years -20°C powder
Beschrijving
Apilimod Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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