ApoA1 Antilichaam

ApoA1 Antibody: Apolipoprotein A1 (ApoA1) is the major protein component of high density lipoprotein (HDL) in plasma, which is correlated with cardiovascular disease. ApoA1 is synthesized in the liver and small intestine and promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT), the enzyme responsible for the formation of most plasma cholesteryl esters. Defects in ApoA1 are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis.

335

P02647

P02647

Human, Chicken

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

ApoA1 Antibody is affinity chromatography purified via peptide column.

Chicken Liver Lysate

1 mg/mL

ApoA1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ApoA1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

APOA1

Apolipoprotein A-I

Homo sapiens

Zhu X, Wu G, Zeng W, et al. Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties. J. Lipid Res. 2005; 46:1303-11

Sorci-Thomas MG, Prack MM, Dashti N, et al. Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins. J. Lipid Res. 1989; 30:1397-403

Lai C-Q, Parnell LD, and Ordovas JM. The APOA1 /C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk. Curr. Opin. Lipid. 2005; 16:153-66

ApoA1 Antibody: Apolipoprotein A-I, Apolipoprotein A1, Apo-AI

ELISA, WB

113992

Liquid