Apoa5 (ab) Antilichaam [1G5G9 (c)

Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.

116519

Q6Q788

Q6Q788

Human

Ni-NTA purified recombinant human APOA5 expressed in E. Coli strain BL21 (DE3) .

1G5G9 (c)

Unconjugated

Primary Antibodies

Signal Transduction

Batch dependent

Purified antibody in PBS containing 0.03% sodium azide.

None

Blue Ice

Apoa5 (ab) monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

APOA5

Apolipoprotein A-V

Homo sapiens

Pennacchio, L, Science 2001. 294, 169-173.

Prieur, X. J Biol Chem 2003. 278, 25468-25480.

RAP3, UNQ411/PRO773, Apolipoprotein A5, Apo-AV, RAP3, APOAV

ELISA, WB

60391728