ApoA5 Antilichaam

ApoA5 Antibody: Apoliproprotein A-V is a protein coded by the APOA5 gene, which is highly expressed in the liver. This protein is responsible for binding to lipids in the liver and forming lipoproteins. In recent years, the gene has been used as a marker for measuring cardiovascular health as well as metabolic syndromes. The protein plays an important role in plasma triglyceride (lipid) regulation within the body. Although only expressed in the liver, APOA5 has functions both inside and outside of cells, as well as modulating triglyceride homeostasis in areas like the gut. Mutations in the APOA5 gene have up to 3 times the risk for the development of cardiovascular disease in association studies. Dietary studies support this lack of metabolic regulation by showing that any mutation in APOA5 will result in higher triglyceride levels than control groups when dieting.

419802

E1BT17

XP_417939

Human, Chicken

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

ApoA5 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1304 - Human Liver Tissue Lysate

1 mg/mL

ApoA5 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ApoA5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

APOA5

Apolipoprotein A-V

Gallus gallus

De Luis Roman et al. Nutrients 2022, 14 (12) : 2427.

Jacob et al. BMC nephrology 2022, 23, 307.

May-Zhang et al. Biochimica et biophysica acta (BBA) - Molecular and cell biology of lipids 2022, 1867 (9) : 159185.

ApoA5 Antibody:

ELISA, WB

118101989

Liquid