ApoM Antilichaam [8F12C6B8]

ApoM (apolipoprotein M, also designated G3a or NG20), with 188-amino acid protein (about 21 kDa), is an apolipoprotein and member of the lipocalin protein family.The Apo-proteins are involved in the specific binding of cellular receptors, the regulation of lipolytic enzymes, and the process of lipid exchange. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport.The N-terminal region of Apo-M contains hydrophobic residues that may promote association with the phospholipid layer of lipoprotein particles. In vitro, Apo-M is glycosylated when translated in the presence of microsomes, and remains associated with the microsomes after carbonate treatment.Apo-M is expressed in liver and kidney, and is secreted into the bloodstream in HDLs, and also found in triglyceride-rich lipoproteins and LDLs.

55937

O95445

O95445

Human

Ni-NTA purified full-length recombinant ApoM.trx expressed in E. Coli strain BL21 (DE3) .

8F12C6B8

Unconjugated

Primary Antibodies

Other

Antibody is purified by protein A affinity chromatography.

Batch dependent

Purified antibody in PBS containing 0.03% sodium azide.

None

Blue Ice

ApoM monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1 & IgG2b

APOM

Apolipoprotein M

Homo sapiens

Xu, N. & Dahlback, B. 1999 J. Biol. Chem. 274:31286.

Duan J, Dahlback B, Villoutreix BO.FEBS Lett. 2001 Jun 15;499 (1-2) :127-32.

Xu, N., Nilsson-Ehle, P. & Ahren, B. 2004. J. Nutr.Biochem. 15 (10) :579-582.

Zhang, X.Y. , et al.2004. Acta Histochem. 106 (2) :123-128

G3A, NG20, HSPC336, Protein G3a, Apo-M, G3a, apo-M

ELISA, WB

17370872