APPL (APPL1) Mouse Monoclonal Antibody [Kloon ID: LBI4B11]

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) APPL1 mouse monoclonal antibody, clone LBI4B11

APPL; DIP13alpha; MODY14

Homo sapiens adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), mRNA.

26060

Q9UKG1

Unconjugated

Colorectal cancer, Pathways in cancer

Colorectal cancer, Pathways in cancer

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

APPL1

https://www.ncbi.nlm.nih.gov/gene/?term=26060

https://www.uniprot.org/uniprot/Q9UKG1