APRT-antilichaam

Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP) . It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

353

P07741

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_000476.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

MCF7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 19-22kDa

IgG

APRT

A-549

K-562

HeLa

Mouse intestine

Adenine phosphoribosyltransferase

Homo sapiens

APRT, AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961, APRTD

WB, IHC

Liquid