AqCbl reductase Antilichaam / Aquacobalamine reductase / MTRR

Dysregulation of AqCbl reductase activity can disrupt cobalamin homeostasis and is associated with metabolic disorders, including methylmalonic acidemia and homocystinuria. Given its pivotal role in cobalamin processing, AqCbl reductase has emerged as a critical marker in studies of vitamin B12 metabolism and related diseases. Researchers have also explored its function in oxidative stress responses and mitochondrial health. The AqCbl reductase antibody enables specific detection of this enzyme in biological samples, supporting studies of cobalamin-dependent metabolic pathways. It is widely used in western blot, immunohistochemistry, and ELISA applications to investigate tissue-specific expression patterns and disease-related changes. With proven performance and high specificity, the AqCbl reductase antibody is an indispensable tool for scientists exploring vitamin B12 metabolism. Incorporating the AqCbl reductase antibody into your research workflow provides valuable insights into the regulation and function of this essential metabolic enzyme.

Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3 µg/mL, Direct ELISA: 0.1-0.5 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Immunoprecipitation: 2ug per 500ug of lysate

Q9UBK8

Human, Mouse, Rat

Recombinant human protein (amino acids L7-S698) was used as the immunogen for the AqCbl reductase antibody.

WB, FACS, IHC-P, IF, Direct ELISA

Antigen affinity purified

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This AqCbl reductase antibody is available for research use only.

After reconstitution, the AqCbl reductase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the AqCbl reductase antibody should be determined by the researcher.

Cytoplasm

Immunofluorescent staining of FFPE human stomach tissue with AqCbl reductase antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH8 EDTA buffer for 20 min.