AR7
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Atypical retinoid which acts as an RARα antagonist and activates chaperone-mediated autophagy (CMA) via an RAR-dependent pathway.1 Downstream signaling results in an increase of LAMP-2A expression.1 Cells pretreated with AR7 had markedly improved viability in a paraquat-induced oxidative stress model.1 AR7 stimulated CMA and attenuated accumulation of SNCA oligomers in prolonged cultures of mutant cortical neurons2 indicating that CMA activation may be a viable disease modifying strategy in Parkinson’s disease3. A targetome analysis of AR7-induced CMA in cancer cells has been performed.4
Unconjugated
Pale pink solid
-20°C
Beschrijving
AR7 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Cellubrevin Antibody
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Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
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1,4- Dioxane Pure
1041330 500
500 mL
Benzonase ELISA Kit
EG23601S
96 Tests
Not I Restriction Enzyme
B2016623
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K562-HLA-G0101 Overexpressing Cell Line
RG-1214
5x 10^6
Yeast Poly (A) Polymerase
RNT-006-S
30000 Units
Recent gezochte producten
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Rat Oxidative Stress Primer Library
ROSL-I
1 set
DTNB (Ellman’s) Thiol Oxidative Stress Assay
1021
1 Kit
OSR1 (Oxidative Stress Responsive 1)
MBS616581-01
0.1 mL
Oxidative Stress Combo Assay Cell Kit
EA-7006
1 Each
Oxidative Stress Combo Assay Blood Kit
EA-7007
1 Each
Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
OSR1 (Oxidative Stress Responsive 1)
O8054
100 µL